Serum 25-hydroxyvitamin D and mental health in young Australian women: Results from the Safe-D study

Abstract

Background While there is evidence linking vitamin D status with mood, this association and its clinical significance remain uncertain. Moreover, few studies have focused on young, community-dwelling females. The Safe-D study examined the association between serum 25-hydroxyvitamin D (25OHD) levels and mental health in young women. Methods Participants completed an online questionnaire, wore a UV dosimeter to measure personal sun exposure and underwent a comprehensive health assessment. Serum 25OHD was measured by liquid chromatography-tandem mass spectrometry in 353 healthy women aged 16–25 years, living in Victoria, Australia. Mental health measures included: Patient Health Questionnaire (..